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NESG statistics
(data retrieved from targetdb and updated weekly)
PSI-2 NESG Protein Production Statistics
| Production stage | | number of targets | | number of constructs |
| Cloned | | 11,447 | | 19,330 |
| Expressed (E > 0) | | 8,596 | | 13,241 |
| Expressed-Soluble (ES >= 10) | | 5,050 | | 6,942 |
| Expressed-Insoluble | | 3,546 |
| 6,299 |
| Purified (>= 0.5 mg yield) | | 2,531 | | 3,249 |
| HSQC spectra recorded | | 1,076 | | 1,445 |
| "Good" or "Promising" HSQC spectra | | 594 | | 799 |
| Crystal hits | | 776 | | 909 |
| Diffraction data collected | | 332 | | 377 |
| Strong-diffracting crystals (< 4 A) | | 289 | | 329 |

| | | | |
| X-ray crystal structures in PDB | | 368 | | |
| NMR structures in PDB | | 271 | | |
| Resonance assignment to BMRB | | 271 | | |
| Distinct targets in PDB | | 579 | | |
| Total structures in PDB | | 639 | | |
PSI-1 & PSI-2 NESG Protein Production Statistics
| Production stage | | number of targets | | number of constructs |
| Cloned | | 16,626 | | 26,631 |
| Expressed (E > 0) | | 11,556 | | 16,703 |
| Expressed-Soluble (ES >= 10) | | 6,773 | | 8,909 |
| Expressed-Insoluble | | 4,783 |
| 7,794 |
| Purified (>= 0.5 mg yield) | | 3,622 | | 4,424 |
| HSQC spectra recorded | | 1,880 | | 2,558 |
| "Good" or "Promising" HSQC spectra | | 949 | | 1,305 |
| Crystal hits | | 995 | | 1,154 |
| Diffraction data collected | | 483 | | 553 |
| Strong-diffracting crystals (< 4 A) | | 433 | | 498 |

| | | | |
| X-ray crystal structures in PDB | | 475 | | |
| NMR structures in PDB | | 355 | | |
| Resonance assignment to BMRB | | 355 | | |
| Distinct targets in PDB | | 755 | | |
| Total structures in PDB | | 830 | | |



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This plot shows Distinct Structures deposited in PDB vs time for each of the four PSI LSCs, and the CESG, a specialized
center that has contributed many structures in the PSI program. "Distinct Structures" have sequences with < 98% seq_id
with any other structure in the PDB on the date of deposition. Multiple crystal forms or nmr/xray pairs count only as a
singleDistinct Structure. |

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Since nmr/xray pairs have unique scientific value, the plot shows numbers of Distinct Structures deposited vs time
counting a nmr and xray structure individually (dotted lines). These NMR/Xray pairs of the same protein, while not formally
"Distinct Structures" have unique value for methods development projects, and provide unique insights into structure-function-dynamic
relationships.
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This plot shows Total PDB depositions vs time for each of the four PSI LSCs, and the CESG. Total Depositions count
each pdb entry; e.g. four crystal structures of a protein bound to 4 different ligands counts as 4 Total Structures.
In this case NMR/Xray pairs count as 2 Total Structures. The entire PSI Program will complete ~ 5000 Total Structures
by the end of Yr 10.
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This plot shows Distinct Structures of Human Proteins deposited in PDB vs time for each of the four PSI LSCs, and the CESG.
Distinct structures have sequences with < 98% id with any other structure in the PDB on the date of deposition.
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This plot shows Distinct Structures of Eukaryotic Proteins deposited in PDB vs time for each of the four PSI LSCs,
and the CESG. Distinct structures have sequences with < 98% id with any other structure in the PDB on the date of deposition.
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This plot shows Distinct Structures of Proteins determined by NMR, deposited in PDB vs time for each of the four PSI LSCs,
and the CESG. Distinct structures have sequences with < 98% id with any other structure in the PDB on the date of deposition.
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